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Ferndale and Foamix Enter Development of an Innovative Foam for the Treatment of Atopic Dermatitis

Ferndale, Michigan and Ness Ziona, Israel, November 5, 2007

Ferndale Laboratories Inc. and Foamix Ltd. announced today that the two companies have signed an agreement to jointly develop a non-steroidal foam for the treatment of atopic dermatitis.

According to this agreement, Foamix will be responsible for developing the foam formulations and Ferndale will have an option to continue definitive development and worldwide commercialization of the product. Additional terms were not disclosed.

Atopic dermatitis is very common in all parts of the world. It affects about 10% of infants and 3% of the total population in the United States. It can occur at any age but is most common in infants to young adults. The skin rash is very itchy and can be widespread or limited to a few areas.

The development of the foam product will be directed to fortify the skin barrier by delivering a very high concentration of barrier-enhancing oils in an easy-to-apply formulation. Non-steroidal therapy is important for safe, long-term management of atopic dermatitis and the associated symptoms. Poor adherence to maintenance treatment for atopic dermatitis and parental anxiety about using topical steroids are common features seen among children with atopic dermatitis, and therefore, foams, which do not need extensive rubbing for spreading and absorption, offer an improved treatment modality for this disease.

“We believe that the Foamix foam offers an effective and convenient way to deliver treatment to patients with atopic dermatitis. These are often very young children who would benefit from the ease and comfort of use, combined with the efficacy of treatment,” said James T. McMillan II, Chief Executive Officer of Ferndale.

“We are very proud to partner with an industry leader such as Ferndale,” said Foamix CEO Dr. Dov Tamarkin. “Foam offers properties that increase usability, encourage compliance and boost user satisfaction. Foamix foams are alcohol-free and they can be designed to provide skin barrier properties, which are crucial for effective atopic dermatitis treatment, while using delicate, FDA approved ingredients, to ensure the safety of the patients,” he noted.

About Ferndale :

Ferndale Ferndale is a specialty pharmaceutical company focused on developing, manufacturing, marketing and selling branded prescription pharmaceutical products in the under-served medical specialties of dermatology, colon/rectal surgery and OB-Gyn.
Read more on www.ferndalelabs.com

About Foamix:

Headquartered in Ness Ziona, Israel, Foamix Ltd. is a specialty pharmaceutical company focused on the development of topical foam products for prescription, OTC and cosmetic applications. Foamix’s state-of-the-art foams provide controlled delivery of a variety of active ingredients. Foamix is a privately held company, whose business model is based on partnering with leading pharma companies to develop products utilizing its proprietary foam technologies. We currently collaborate with 8 pharmaceutical companies on 10 projects in the development of proprietary dermatological and gynecologic foam drugs; and we have our own in-house pipeline of dermatological and gynecological drugs in foam presentation.
The company’s development capabilities range from initial development of foam formulations to scale-up, GMP manufacturing, preclinical and clinical studies. Foamix holds 3 US patents and has 48 US patents pending, with corresponding national applications worldwide.
For additional information please visit www.foamix.co.il.
Press inquiries: Sigal Maymon, Foamix Ltd, +972-8-9316233 or info@foamix.co.il