GyneFoamix-Proprietary foam formulations of gynecological drugs at Foamix

Many vulvo-genital disorders require topical therapy which is done today using suppositories, creams and ointments. Due to the nature of the target site, such vehicle does not provide sufficient coverage of the afflicted area, and thus, their efficacy is insufficient.

GyneFoamix products, comprising gynecological drugs in expandable foam formulations are delivered into the vagina and upon release, cover the afflicted surface effectively, thus providing favorable therapeutic results.

GyneFoamix™ is useful for a variety of female disorders:

Lower Genital Tract Disorders

Candidal Vaginitis

Drugs: Azoles (e.g.,Miconazole & Clotrimazole)

Bacterial Vaginosis

Drugs: Antibiotics - Metronidazole & Clindamycin

Vaginal Dryness

Therapy: Hormone, Lubricants, Moisturizing Agents

Acute and Chronic Vulvitis (Pelvic Pain)

Drug: Corticosteroids; Antihistamins; Local Anesthetics

Herpes Simplex & Genital Ulcers

Drugs: Acyclovir, Famciclovir, Valacyclovir

HPV Genital Warts
Hormonal Therapy

Vulvar Disorders

Contact Dermatitis

Yeast Infections

Sexually Transmitted Diseases

Genital Warts (condyloma)

Genital Herpes

Many drugs can be incorporated in the GyneFoamix foam vehicle, including:

Antifungals

Antibiotics

Steroids/hormones

Local anesthetics

Anticancer drugs

Drugs for labor enhancement

Clear advantages vs. current therapy (see comparison table)

One step administration

Convenient insertion

Easy removal

Accurate dose

No leak

Effective area of contact

Any drug can be included - water soluble, oil soluble and suspension

Residence time can be controlled: bio-adhesion and phase change polymers

Partnering
Foamix has completed the development of a number of such products, which are ready for either marketing or advanced development, worldwide.

Foamix is actively seeking development and marketing partners for products from the GyneFoamix™ platform.